AMDZone has some new on OpenVMS. From this page it looks as if though HP plans to port OpenVMS to AMD64.
.9 Why hasn't OpenVMS been ported to Intel (IA-32) systems?
Why? Business reasons...
There is presently a belief that there would be insufficient market to justify the cost involved in porting OpenVMS to systems using the Intel IA-32 architecture. In addition to the direct costs involved in any port, each maintainer of a product or a package for OpenVMS has to justify the port to "OpenVMS Pentium" or to OpenVMS Itanium, akin to the required justifications for a product port from OpenVMS VAX to OpenVMS Alpha.
But yes, it would be nice to have.
And yes, OpenVMS Engineering is well aware of AMD Opteron/Hammer, too.
More info @ HP